UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D

Under the Securities Exchange Act of 1934
(Amendment No. 5)*

Alkermes Public Limited Company
(Name of Issuer)
 
Ordinary shares, $0.01 par value
(Title of Class of Securities)
 
G01767105
(CUSIP Number)
 
Mark DiPaolo
Senior Partner, General Counsel
Sarissa Capital Management LP
660 Steamboat Road
Greenwich, CT 06830
203-302-2330
(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
 
July 6, 2022
(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box. ☐
Note:  Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.
*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).





CUSIP No. G01767105
Page 2 of  5  Pages
SCHEDULE 13D

1
NAME OF REPORTING PERSON OR
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Sarissa Capital Management LP
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a) ☐   
(b) ☐   
3
SEC USE ONLY
 
 
4
SOURCE OF FUNDS

WC
5
CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
 
 
 ☐
6
CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7
SOLE VOTING POWER

0
8
SHARED VOTING POWER

14,040,000
9
SOLE DISPOSITIVE POWER

0
10
SHARED DISPOSITIVE POWER

14,040,000
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,040,000
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES:
 ☐

13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

8.55%
14
TYPE OF REPORTING PERSON
 
PN


CUSIP No. G01767105
Page 3 of  5  Pages
SCHEDULE 13D


1
NAME OF REPORTING PERSON OR
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Alexander J. Denner, Ph.D.
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)   ☐ 
(b)   ☐
3
SEC USE ONLY
 
 
4
SOURCE OF FUNDS

WC
5
CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
 
 
 ☐
6
CITIZENSHIP OR PLACE OF ORGANIZATION

United States
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7
SOLE VOTING POWER

0
8
SHARED VOTING POWER

14,040,000
9
SOLE DISPOSITIVE POWER

0
10
SHARED DISPOSITIVE POWER

14,040,000
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

14,040,000
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES:
 ☐

13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

8.55%
14
TYPE OF REPORTING PERSON
 
IN





CUSIP No. G01767105
Page 4 of  5  Pages
SCHEDULE 13D

This Amendment No. 5 to Schedule 13D (“Amendment No. 5”) relates to ordinary shares, par value $0.01 per share (“Common Stock” and, such shares, the “Shares”), issued by Alkermes Public Limited Company, a company incorporated under the laws of Ireland (the “Issuer”), and amends the initial statement on Schedule 13D filed with the Securities and Exchange Commission (the “SEC”) on May 10, 2021 (the “Initial Schedule 13D”), as amended by Amendment No. 1 to Schedule 13D filed on May 27, 2021 (“Amendment No. 1”), Amendment No. 2 to Schedule 13D filed on September 10, 2021 (“Amendment No. 2”), Amendment No. 3 to Schedule 13D filed on November 19, 2021 (“Amendment No. 3”) and Amendment No. 4 to Schedule 13D filed on January 10, 2022 (“Amendment No. 4” and together with the Initial Schedule 13D, Amendment No. 1, Amendment No. 2 and Amendment No. 3, the “Schedule 13D”), on behalf of the Reporting Persons, to furnish the additional information set forth herein. All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule 13D.
Item 4.  Purpose of Transaction. Item 4 of the Schedule 13D is hereby amended to include the following:
On July 6, 2022, Sarissa Capital issued a press release indicating how the Reporting Persons intend to vote at the upcoming annual meeting of the Issuer and the reasons therefor. A copy of the press release is attached as Exhibit 3 hereto.
Item 5.  Interest in Securities of the Issuer. Item 5 (a) of the Schedule 13D is hereby amended and restated as follows:
(a) The Reporting Persons may be deemed to beneficially own, in the aggregate, 14,040,000 Shares representing approximately 8.55% of the outstanding Shares, based upon the 164,136,728 Shares outstanding as of June 1, 2022, as set forth in the definitive proxy statement of the Issuer filed with the U.S. Securities and Exchange Commission on June 6, 2022.
Item 7. Material to Be Filed as Exhibits. Item 7 of the Schedule 13D is hereby amended to include the following:
Exhibit 3 – Press Release, July 6, 2022


CUSIP No. G01767105
Page 5 of  5  Pages
SCHEDULE 13D
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct.

Dated:  July 6, 2022

SARISSA CAPITAL MANAGEMENT LP


By:         /s/ Mark DiPaolo _______________________
 Name: Mark DiPaolo
 Title: Senior Partner, General Counsel


/s/Alexander J. Denner________________________
Alexander J. Denner



EXHIBIT 3

SARISSA CAPITAL COMMENTS ON ALKERMES ANNUAL MEETING

Sarissa concerned that Alkermes Board is being unduly influenced by CEO Richard Pops

Sarissa supports new Alkermes directors to step up and act for the benefit of shareholders

Sarissa is considering taking action under Irish law to selectively remove and replace Alkermes directors

Greenwich, CT, July 6, 2022 – Sarissa Capital Management LP (“Sarissa”) today made the following statement on Alkermes PLC (NASDAQ: ALKS) regarding how it intends to vote at the upcoming Alkermes annual meeting and the reasons therefor:

Richard Pops, the CEO and Chairman of Alkermes, has presided over tremendous shareholder value destruction since becoming CEO of Alkermes over thirty years ago.  Despite Alkermes growing revenues in the last five years and having annual revenues exceeding $1 billion, Alkermes has consistently operated at a net loss.  During the same period, Alkermes stock has declined nearly 60% and underperformed the IBB by approximately 130%.1

Based on conversations with CEO Pops and its experience to date with the Alkermes nomination and governance process, Sarissa believes that certain of the independent directors are uncomfortable making decisions that are not supported by, or that reflect criticism of, CEO Pops.
 
Alex Denner and Richard Pops and others have had a number of conversations which we were hopeful would lead to a Sarissa representative working on the Alkermes board to create value for all shareholders.  Unfortunately, Pops set forth a version of these conversations in the Alkermes’ securities filings which is fraught with misleading statements, inaccuracies and material omissions.  We believe Alkermes’ alleged detailed summary of our communications is counterproductive, unprofessional, and more importantly, it is blatantly and materially incorrect. In addition, we believe that a policy of releasing misleading summaries of our private conversations is low class. We caution others having seemingly private conversations with Richard Pops that he may be taking notes of each conversation that he intends to later release to the public in a self-serving and misleading way.      

Sarissa believes that its support of the recently appointed directors combined with the decisions of long tenured directors Anstice and Dixon, to not stand for re-election, should create an environment in the board room that will enable the directors to do the right thing for shareholders even in the face of resistance from Pops.   

It is apparent to us that Richard Pops is trying very hard to keep a Sarissa person off the board of the company even though we own nearly $450 million in Alkermes stock.  We believe he is worried that once in the boardroom we may decide that a new CEO would be better at creating value for shareholders than Richard Pops.  As one of the largest shareholders, Sarissa has a vested interest in Alkermes’ success. We have a long history of creating value for our companies. We believe Alkermes’ shares are significantly undervalued and that we can help to unlock shareholder value with our representatives on the board. We are hopeful that the current board will agree with us.

Therefore, we intend to vote “for” the Alkermes slate of directors (which consists entirely of recently appointed directors) at the upcoming annual meeting.  If, however, a Sarissa representative is not soon appointed to the Alkermes board, then we will take steps under Irish law to quickly call another shareholder meeting that seeks to selectively remove and replace certain board members with those that Sarissa believes will act in the best interest of shareholders. 
 
Contact: 
Jean Puong
Sarissa Capital Management LP
info@sarissacap.com




1 Estimated by subtracting the percentage change of Alkermes’ share price from the percentage change of IBB price from 12/30/16 to 12/30/21.